Splenic Infarction with Aortic Thrombosis in COVID-19

Am J Med Sci. 2021 Oct;362(4):418-423. doi: 10.1016/j.amjms.2021.06.007. Epub 2021 Jun 20.

Abstract

Coronavirus disease 2019 (COVID-19) has been associated with an increased risk of venous and arterial thrombotic disease. Although pulmonary embolism has been the most common thrombotic complication, there have been recent reports of COVID-19-associated large-vessel ischemic stroke, acute upper- and lower-limb ischemia, as well as infarctions of the abdominal viscera, including renal, splenic, and small bowel infarctions. Here, we describe a case of splenic infarction (SI) associated with aortic thrombosis, which evolved despite the prophylactic use of low-molecular-weight heparin (LMWH), in a 60-year-old female patient with COVID-19. The patient was treated clinically with a therapeutic dose of LMWH, followed by warfarin, and eventually presented a favorable outcome. We also present a review of the literature regarding SI in patients with COVID-19.

Keywords: Aorta; Covid-19; Spleen; Splenic infarction; Thrombosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aortic Diseases / virology*
  • COVID-19 / complications*
  • COVID-19 / diagnostic imaging
  • Computed Tomography Angiography
  • Female
  • Humans
  • Middle Aged
  • Splenic Infarction / diagnostic imaging
  • Splenic Infarction / virology*
  • Thrombosis / virology*