LncRNAs and Available Databases

Methods Mol Biol. 2021:2348:3-26. doi: 10.1007/978-1-0716-1581-2_1.

Abstract

Long noncoding RNAs (lncRNAs) are involved in many regulatory mechanisms in practically every step of the RNA cycle, from transcription to RNA stability and translation. They are a highly heterogeneous class of molecules in terms of site of production, interaction networks, and functions. More and more databases are available on the web with the aim to make public information about lncRNA accessible to the scientific community. Here we review the most interesting resources with the purpose to organize a compendium of useful tools to interrogate before studying a lncRNA of interest.

Keywords: Database; Disease association; In silico prediction; Protein interaction; lncRNA; miRNA interaction.

Publication types

  • Review

MeSH terms

  • Chromosome Mapping
  • Databases, Genetic*
  • Disease Susceptibility
  • Gene Expression Regulation
  • Gene Regulatory Networks
  • Humans
  • MicroRNAs / genetics
  • RNA, Long Noncoding / genetics*
  • RNA, Long Noncoding / metabolism
  • RNA, Messenger / genetics
  • Web Browser

Substances

  • MicroRNAs
  • RNA, Long Noncoding
  • RNA, Messenger