Using data mining technology to predict medication-taking behaviour in women with breast cancer: A retrospective study

Nurs Open. 2022 Nov;9(6):2646-2656. doi: 10.1002/nop2.963. Epub 2021 Jun 22.

Abstract

Aims: Medication-taking behaviours of breast cancer survivors undergoing adjuvant hormone therapy have received considerable attention. This study aimed to determine factors affecting medication-taking behaviours in people with breast cancer using data mining.

Design: A longitudinal observational retrospective cohort study with a hospital-based survey.

Methods: A total of 385 subjects were surveyed, analysing existing data from January 2010 to December 2017 in Taiwan. Three data mining approaches-multiple logistic regression, decision tree and artificial neural network-were used to build the prediction models and rank the importance of influencing factors. Accuracy, specificity and sensitivity were used as assessment indicators for the prediction models.

Results: Multiple logistic regression was the most effective approach, achieving an accuracy of 96.37%, specificity of 96.75% and sensitivity of 96.12%. The duration of adjuvant hormone therapy discontinuation, duration of adjuvant hormone therapy use and age at diagnosis by data mining were the three most critical factors influencing the medication-taking behaviours of people with breast cancer.

Keywords: adherence; breast cancer; data mining; medication-taking behaviours; persistence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Hormonal / therapeutic use
  • Breast Neoplasms* / drug therapy
  • Chemotherapy, Adjuvant
  • Data Mining
  • Female
  • Hormones / therapeutic use
  • Humans
  • Medication Adherence
  • Retrospective Studies
  • Technology

Substances

  • Antineoplastic Agents, Hormonal
  • Hormones