Osteonecrosis of the Femoral Head: an Updated Review of ARCO on Pathogenesis, Staging and Treatment

J Korean Med Sci. 2021 Jun 21;36(24):e177. doi: 10.3346/jkms.2021.36.e177.

Abstract

Non-traumatic osteonecrosis of the femoral head (ONFH) usually affects adults younger than 50 years and frequently leads to femoral head collapse and subsequent arthritis of the hip. It is becoming more prevalent along with increasing use of corticosteroids for the adjuvant therapy of leukemia and other myelogenous diseases as well as management of organ transplantation. This review updated knowledge on the pathogenesis, classification criteria, staging system, and treatment of ONFH.

Keywords: Avascular Necrosis; Femoral Head; Hip; Osteonecrosis.

Publication types

  • Review

MeSH terms

  • Femur Head / pathology*
  • Femur Head Necrosis / classification*
  • Femur Head Necrosis / pathology*
  • Glucocorticoids / adverse effects*
  • Hip / pathology*
  • Humans
  • Osteonecrosis / pathology
  • Osteonecrosis / therapy*
  • Prednisolone / adverse effects

Substances

  • Glucocorticoids
  • Prednisolone