Update on female urethral reconstruction

Curr Opin Urol. 2021 Sep 1;31(5):486-492. doi: 10.1097/MOU.0000000000000907.

Abstract

Purpose of review: Female urethral stricture (FUS) is not frequent but can be the cause of significant morbidity. A somewhat overlooked condition for years, it has received significant attention in recent times. In this review, we update the current evidence surrounding FUS management.

Recent findings: It is estimated that FUS is present in about 1% of all women having check-ups for lower urinary tract symptoms. Etiology is considered as idiopathic in half of the cases, iatrogenic in one-third, whereas infection/inflammation and trauma account for the rest. Symptoms presented are usually nonspecific and nondiagnostic. Pelvic examination, uroflowmetry, endoscopy, and urethrography are the most frequently employed diagnostic tools. Urodynamics/video-urodynamics can be used to document obstruction and to differentiate true anatomic strictures from functional disorders. Urethral dilation (UD) is the most frequent management procedure, sometimes followed by self-dilation, but recurrence is high, at over 50%. By contrast, reconstructive surgery is far more efficient, with overall curative rates of around 90%.

Summary: A high index of suspicion is required to identify FUS patients. UD is advised as a first approach but after one or two failed attempts, reconstruction at a referral center should be considered.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Plastic Surgery Procedures*
  • Urethra / diagnostic imaging
  • Urethra / surgery
  • Urethral Stricture* / diagnostic imaging
  • Urethral Stricture* / surgery
  • Urodynamics
  • Urologic Surgical Procedures / adverse effects