Abstract
A π-conjugated porous organic polymer (BCzBz) was fabricated employing N,N'-bicarbazole and benzothiadiazole as molecular building units exhibiting broad visible light absorption. The photostable, water-dispersible, and cytocompatible BCzBz was demonstrated as an efficient probe for intracellular reactive oxygen species generation under photoirradiation.
MeSH terms
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Antineoplastic Agents / chemical synthesis
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Antineoplastic Agents / pharmacology*
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Antineoplastic Agents / radiation effects
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Carbazoles / chemical synthesis
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Carbazoles / pharmacology*
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Carbazoles / radiation effects
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HeLa Cells
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Humans
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Light
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Photosensitizing Agents / chemical synthesis
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Photosensitizing Agents / pharmacology*
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Photosensitizing Agents / radiation effects
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Polymers / chemical synthesis
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Polymers / pharmacology*
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Polymers / radiation effects
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Porosity
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Reactive Oxygen Species / metabolism*
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Thiadiazoles / chemical synthesis
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Thiadiazoles / pharmacology*
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Thiadiazoles / radiation effects
Substances
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Antineoplastic Agents
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Carbazoles
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Photosensitizing Agents
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Polymers
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Reactive Oxygen Species
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Thiadiazoles