Aminopyrifen, a novel 2-aminonicotinate fungicide with a unique effect and broad-spectrum activity against plant pathogenic fungi

Masahiro Hatamoto; Ryo Aizawa; Kogomi Koda; Toshiki Fukuchi

doi:10.1584/jpestics.D20-094

Aminopyrifen, a novel 2-aminonicotinate fungicide with a unique effect and broad-spectrum activity against plant pathogenic fungi

J Pestic Sci. 2021 May 20;46(2):198-205. doi: 10.1584/jpestics.D20-094.

Authors

Masahiro Hatamoto¹, Ryo Aizawa², Kogomi Koda¹, Toshiki Fukuchi¹

Affiliations

¹ Biological Section Research Department, AGRO-KANESHO Co., Ltd., 9511-4, Yuki Ibaraki 307-0001, Japan.
² Chemical Synthesis Section Research Department, AGRO-KANESHO Co., Ltd., Tokorozawa, Saitama 359-0024, Japan.

Abstract

Aminopyrifen is a novel 2-aminonicotinate fungicide with unique chemistry and a novel mode of action. The fungicide showed high antifungal activity mainly against Ascomycetes and its related anamorphic fungi under in vitro and pot conditions (EC₅₀ values: 0.0039-0.23 mg/L and 1.2-12 mg/L, respectively). The active ingredient strongly inhibited germ-tube elongation of Botrytis cinerea below 0.1 mg/L and invasion into a plant. The compound exhibited no cross-resistance to commercial fungicides in B. cinerea. The antifungal agent showed high preventive efficacy and translaminar action. In the field, aminopyrifen controlled gray mold and powdery mildew at 150 mg/L. Our findings suggest that aminopyrifen is useful for protecting crops from various plant pathogens.

Keywords: 2-aminonicotinate fungicide; GPI; GWT-1 inhibitor; aminopyrifen; gray mold.

© Pesticide Science Society of Japan 2021. This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License (https://creativecommons.org/licenses/by-nc-nd/4.0/).