Management of optic disc pit-associated maculopathy: A case series from a tertiary referral center

Eur J Ophthalmol. 2022 May;32(3):1720-1727. doi: 10.1177/11206721211023727. Epub 2021 Jun 16.

Abstract

Purpose: To report outcomes of pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) stuffing technique in patients with optic disc pit associated maculopathy (ODP-M).

Methods: Data including best-corrected visual acuity (BCVA), central macular thickness (CMT), foveal center point thickness (FCP), and maximum height of fluid (max_fluid) (intraretinal or subretinal) were collected from the medical records of the patients.

Results: Six eyes of six patients with a mean age of 28.0 ± 17.68 years (range: 9-53 year) underwent PPV + ILM plug surgery. The mean follow-up duration was 25.62 ± 26.11 months (range: 11.80-78.00 month) duration. The mean BCVA increased from 1.25 ± 1.04 logMAR (20/355, Snellen equivalent) to 0.86 ± 1.09 logMAR (20/144, Snellen equivalent) at last follow-up (p = 0.043). Compared to baseline, CMT, FCP, and max_fluid significantly decreased at all visits after the surgery (p < 0.05 for all visits). At last follow-up, 66.6% of the eyes (four eyes) showed complete resolution of fluid at a mean of 5.25 ± 4.99 months (range: 1-12 months) after the surgery.

Conclusion: PPV with ILM plug seemed to be an effective surgical technique in ODP-M. Studies with longer follow-up and higher number of patients are needed to confirm our results.

Keywords: ODP maculopathy; Optic pit; PPV; optic pit maculopathy; vitrectomy.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Eye Abnormalities* / complications
  • Eye Abnormalities* / diagnosis
  • Eye Abnormalities* / surgery
  • Follow-Up Studies
  • Humans
  • Macular Degeneration* / surgery
  • Middle Aged
  • Optic Disk*
  • Retinal Diseases* / surgery
  • Retrospective Studies
  • Tertiary Care Centers
  • Tomography, Optical Coherence / methods
  • Vitrectomy / methods
  • Young Adult