Fatal necrotising cutaneous mucormycosis due to novel Saksenaea species: a case study

J Wound Care. 2021 Jun 2;30(6):465-468. doi: 10.12968/jowc.2021.30.6.465.

Abstract

This case report describes the progressive wound infection in the left thigh of a 34-year-old man due to an old landmine explosion. The infection developed into rapidly spreading skin and soft tissue necrotising Saksenaea infection, despite antifungal therapy and surgical debridement. The report provides evidence that Saksenaea spp. should be added to the list of mucoralean fungi that can cause severe necrotising infection. It also highlights the need for improved early diagnostic procedures and enhanced understanding of Saksenaea virulence factors that contribute to necrotising infection.

Keywords: Saksenaea species; cutaneous mucormycosis; infection; mucorales; mucormycosis; necrosis; trauma; wound; wound healing; zygomycosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antifungal Agents / therapeutic use
  • Dermatomycoses / diagnosis
  • Dermatomycoses / drug therapy
  • Fatal Outcome
  • Humans
  • Male
  • Mucorales / isolation & purification*
  • Mucormycosis / diagnosis*
  • Necrosis*
  • Wound Infection* / drug therapy

Substances

  • Antifungal Agents

Supplementary concepts

  • Saksenaea erythrospora
  • Saksenaea infection