The role of hemostatic devices in neurosurgery. A systematic review

J Clin Neurosci. 2021 Jul:89:151-157. doi: 10.1016/j.jocn.2021.05.016. Epub 2021 May 12.

Abstract

Hemostasis represents a fundamental step in every surgical procedure. During neurosurgical procedures, proper and robust hemostasis into confined spaces can significantly reduce the odds of perioperative complications. Over the decades, multiple methods have been applied, and several medical devices have been developed to promote and guarantee proper hemostasis. This study presents a systematic review of the most used intraoperative hemostatic methods and devices in neurosurgery. Insightful research was performed on the PubMed database according to the PRISMA guidelines. This comprehensive review of scientific literature represents a synoptic panel where the most used intraoperative hemostatic methods and devices available today in neurosurgery are classified and described.

Keywords: Bone wax; Fibrin sealants; Gelatin foam; Gelatin sponges; Microfibrillar collagen; Oxidized cellulose; Platelet-rich plasma.

Publication types

  • Systematic Review

MeSH terms

  • Hemostasis / drug effects*
  • Hemostasis / physiology
  • Hemostasis, Surgical / methods*
  • Hemostatics / pharmacology
  • Hemostatics / therapeutic use*
  • Humans
  • Nervous System Diseases / drug therapy
  • Nervous System Diseases / surgery
  • Neurosurgical Procedures / methods*

Substances

  • Hemostatics