BCKDK: an emerging kinase target for metabolic diseases and cancer

Nat Rev Drug Discov. 2021 Jul;20(7):498. doi: 10.1038/d41573-021-00107-6.
No abstract available

MeSH terms

  • 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) / antagonists & inhibitors*
  • Amino Acids, Branched-Chain / metabolism
  • Antineoplastic Agents / therapeutic use*
  • Drug Delivery Systems
  • Enzyme Inhibitors / therapeutic use*
  • Humans
  • Metabolic Diseases / drug therapy*
  • Metabolic Diseases / enzymology
  • Neoplasms / drug therapy*
  • Neoplasms / enzymology

Substances

  • Amino Acids, Branched-Chain
  • Antineoplastic Agents
  • Enzyme Inhibitors
  • 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)