Current and novel multi-imaging modalities to assess retinal oxygenation and blood flow

Eye (Lond). 2021 Nov;35(11):2962-2972. doi: 10.1038/s41433-021-01570-6. Epub 2021 Jun 11.

Abstract

Retinal ischemia characterizes the underlying pathology in a multitude of retinal diseases that can ultimately lead to vision loss. A variety of novel imaging modalities have been developed to characterize retinal ischemia by measuring retinal oxygenation and blood flow in-vivo. These technologies offer valuable insight into the earliest pathophysiologic changes within the retina and provide physicians and researchers with new diagnostic and monitoring capabilities. Future retinal imaging technologies with the capability to provide affordable, noninvasive, and comprehensive data on oxygen saturation, vasculature, and blood flow mechanics are needed. This review will highlight current and future trends in multimodal imaging to assess retinal blood flow and oxygenation.

摘要: 视网膜缺血是多种视网膜疾病的基本病理特征, 最终可导致视力丧失。目前已有多种新的影像学成像技术通过测量体内视网膜氧合水平以及血流来诊断视网膜缺血。这些技术为监测视网膜最早的病理生理变化提供了有价值的信息, 并为医生和研究人员提供了新的诊断和监测疾病的能力。未来的视网膜成像技术在氧饱和度以及血管系统和血流力学方面不仅使患者可以负担得起、无创并且可以提供更加全面的数据。本文将重点强调多模态成像技术平台评估视网膜血流以及氧合水平的目前状态以及未来的趋势。.

Publication types

  • Review

MeSH terms

  • Diagnostic Imaging
  • Humans
  • Oxygen*
  • Regional Blood Flow
  • Retina / diagnostic imaging
  • Retinal Diseases* / diagnostic imaging

Substances

  • Oxygen