Biologics in Otolaryngology: Past, Present, and Future

Nicole C Schmitt; Ashkan Monfared; Sarah K Wise

doi:10.1016/j.otc.2021.04.001

Biologics in Otolaryngology: Past, Present, and Future

Otolaryngol Clin North Am. 2021 Aug;54(4):675-687. doi: 10.1016/j.otc.2021.04.001. Epub 2021 Jun 9.

Authors

Nicole C Schmitt¹, Ashkan Monfared², Sarah K Wise³

Affiliations

¹ Head and Neck Cancer Program, Department of Otolaryngology - Head and Neck Surgery, Winship Cancer Institute, Emory University School of Medicine, 550 Peachtree Street Northeast, 11th Floor Otolaryngology, Atlanta, GA 30308, USA. Electronic address: nicole.cherie.schmitt@emory.edu.
² Division of Otolaryngology - Head and Neck Surgery, George Washington University, Washington, DC 20052, USA.
³ Department of Otolaryngology - Head and Neck Surgery, Emory University School of Medicine, 550 Peachtree Street Northeast, 11th Floor Otolaryngology, Atlanta, GA 30308, USA.

PMID: 34116845
DOI: 10.1016/j.otc.2021.04.001

Abstract

Biologics have been widely adopted in multiple subspecialties of otolaryngology. This article provides an overview of past, present, and future uses of biologics in otolaryngology with emphasis on allergic rhinitis, chronic rhinosinusitis with polyposis, head and neck squamous cell carcinoma, salivary and skull base tumors, hearing loss, and other otologic disorders.

Keywords: Allergy; Biologics; Cancer; Immunotherapy; Monoclonal antibodies; Nasal polyposis; Otolaryngology; Rhinosinusitis.

Publication types

Review

MeSH terms

Biological Products* / therapeutic use
Chronic Disease
Humans
Nasal Polyps*
Otolaryngology*
Rhinitis* / drug therapy
Sinusitis*

Substances

Biological Products