Burkitt Lymphoma/Leukemia Presented on 68Ga-Pentixafor and 18F-FDG PET/CT

Clin Nucl Med. 2022 Jan 1;47(1):98-100. doi: 10.1097/RLU.0000000000003750.

Abstract

An 18-year-old man with newly diagnosed Burkitt lymphoma/leukemia was referred for 18F-FDG and 68Ga-Pentixafor PET/CT. 68Ga-Pentixafor PET/CT revealed similar radioactivity uptake pattern to the 18F-FDG PET/CT in superior phrenic lymph node, ascending colon, ileocecum, peritoneal, marrow, and spleen. This case highlighted that it might be interesting to further investigate the role of 68Ga-Pentixafor PET/CT imaging in staging, treatment evaluation, and especially the feasibility of CXCR4-directed radioligand therapy in Burkitt lymphoma with positive expression of CXCR4.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Burkitt Lymphoma* / diagnostic imaging
  • Coordination Complexes
  • Fluorodeoxyglucose F18
  • Humans
  • Leukemia*
  • Male
  • Peptides, Cyclic
  • Positron Emission Tomography Computed Tomography

Substances

  • 68Ga-pentixafor
  • Coordination Complexes
  • Peptides, Cyclic
  • Fluorodeoxyglucose F18