Selective C-H Iodination of (Hetero)arenes

Org Lett. 2021 Jul 2;23(13):5024-5027. doi: 10.1021/acs.orglett.1c01530. Epub 2021 Jun 11.

Abstract

Iodoarenes are versatile intermediates and common synthetic targets in organic synthesis. Here, we present a strategy for selective C-H iodination of (hetero)arenes with a broad functional group tolerance. We demonstrate the utility and differentiation to other iodination methods of supposed sulfonyl hypoiodites for a set of carboarenes and heteroarenes.