Novel coronavirus disease 2019 (COVID-19) has started to erupt in Wuhan since December 2019, and then the cases of COVID-19 increased rapidly, the epidemic situation spreaded to most area of China. Owing to the lack of specific drugs at present, convalescent plasma therapy becomes an alternative treatment. However, the choice of the donor, suitable patients, timing of treatment, administrate dose, the advantages and disadvantages of the treatment are not clear. This article reviews the clinical studies and case reports of convalescent plasma therapy in several previous viral infectious diseases in order to provide clues for the treatment of COVID-19.
题目: 康复期血浆输注对暴发性病毒性传染病的治疗作用.
摘要: 自2019年12月开始出现新型冠状病毒感染肺炎（COVID-19）病例以来，数月内确认病例数迅速增加，疫情扩散至国内大部分地区。鉴于此次COVID-19暴发时缺乏明确的特效药物，新型冠状病毒感染肺炎患者康复期血浆治疗成为一种可选择的治疗方案。然而，对于其中供体的选择、适合治疗的患者、治疗的时机选择、输注剂量以及优势和缺点等不甚明确。本文就康复期血浆治疗在之前数种病毒性传染病流行期的临床研究以及病例报告中提示的以上问题作一综述，期望能对此次COVID-19的治疗提供线索.