Effects of non-invasive respiratory support on sleep in preterm infants evaluated by actigraphy

Fernanda Schmidt; Felipe Kalil Neto; Graciane Radaelli; Magda Lahorgue Nunes

doi:10.5935/1984-0063.20200035

Effects of non-invasive respiratory support on sleep in preterm infants evaluated by actigraphy

Sleep Sci. 2021 Jan-Mar;14(1):72-76. doi: 10.5935/1984-0063.20200035.

Authors

Fernanda Schmidt¹, Felipe Kalil Neto², Graciane Radaelli³, Magda Lahorgue Nunes^{3

4}

Affiliations

¹ Universidade Luterana do Brasil, Department of Neonatology - Canoas - RS - Brazil.
² Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul, Department of Neurology - Porto Alegre - RS - Brazil.
³ Brain Institute of Rio Grande do Sul - Porto Alegre - RS - Brazil.
⁴ Escola de Medicina da Pontificia Universidade Catolica do Rio Grande do Sul - Porto Alegre - RS - Brazil.

Abstract

Objective: Few studies have evaluated sleep in preterm infants under non-invasive ventilatory support in neonatal intensive care units (NICU). The main objective of this study was to evaluate the inﬂuence of continuous positive airway pressure (CPAP) in the sleep of premature babies.

Material and methods: Crossover study in a NICU. We selected preterm infants with gestational age between 28 and 37 weeks using nasal CPAP. Eighteen preterm were included. Patients were monitored with actigraphy and with the Neonatal Behavioral Assessment Scale (NBAS).

Results: Results showed a reduction in sleep effciency, total sleep time and total sleep period during the CPAP period when compared to the non-CPAP. NBAS demonstrated signiﬁcantly greater time of deep sleep and light sleep in the period without CPAP.

Conclusion: Our data suggests that the use of CPAP, during the ﬁrst week of life, in preterm neonates, is associated with transitory alterations of sleep organization.

Keywords: Actigraphy; Infant; Premature; Sleep.

Grants and funding

MLN is supported by the Grant PQ 306338/2017-3 from CNPq - Brazil. This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brazil - (CAPES) - Finance Code 001, through a scholarship received by FS.