Short-term monocular deprivation induces an interocular delay

Abstract

Short term monocular deprivation modulates ocular dominance, such that the previously deprived eye's contribution to the binocular percept increases, supposedly as a result of changes in contrast-gain. Therefore, the processing time of the previously patched eye would be expected to speed up as a result of an increase in contrast gain. In order to test this hypothesis, this study examines the effects of short-term monocular deprivation on interocular synchronicity. The present study uses a paradigm based on the Pulfrich phenomenon. The stimulus used for testing consists of elements defining a cylinder rotating in depth, that allows measurement of any interocular delay. The interocular delay was measured at baseline before patching and at outcome, after one hour of monocular deprivation with an opaque or translucent patch. Contrary to expectations, short-term monocular deprivation induces an interocular delay, albeit not always significant, in the previously patched eye. The amplitude of this effect is larger with opaque patching compared to translucent patching. These results are the first report of a non-beneficial effect - i.e. a slowing down in the processing time of the previously patched-eye. They indicate that the plasticity effects of monocular deprivation are not exclusively mediated by contrast gain mechanisms and that light adaptation mechanisms might also be involved in the plasticity resulting from short-term monocular deprivation.

Keywords: Binocular vision; Interocular delay; Motion-in-depth; Patching; Pulfrich phenomenon; Short-term monocular deprivation.