A single mutation underlying phenotypic convergence for hypoxia adaptation on the Qinghai-Tibetan Plateau

Dongming Xu; Cuiping Yang; Qiushuo Shen; Shengkai Pan; Zhen Liu; Tongzuo Zhang; Xin Zhou; Menglong Lei; Peng Chen; Hui Yang; Tao Zhang; Yuanting Guo; Xiangjiang Zhan; Yongbin Chen; Peng Shi

doi:10.1038/s41422-021-00517-6

A single mutation underlying phenotypic convergence for hypoxia adaptation on the Qinghai-Tibetan Plateau

Cell Res. 2021 Sep;31(9):1032-1035. doi: 10.1038/s41422-021-00517-6. Epub 2021 Jun 7.

Authors

Dongming Xu^#¹, Cuiping Yang^#², Qiushuo Shen^#², Shengkai Pan^#³, Zhen Liu^#^{1

4}, Tongzuo Zhang^#^{5

6}, Xin Zhou¹, Menglong Lei¹, Peng Chen^{1

7}, Hui Yang¹, Tao Zhang^{1

7}, Yuanting Guo^{1

7}, Xiangjiang Zhan^{8

9}, Yongbin Chen^{10

11}, Peng Shi^{12

13

14}

Affiliations

¹ State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.
² Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China.
³ Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
⁴ Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, Yunnan, China.
⁵ Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, Qinghai, China.
⁶ Qinghai Provincial Key Laboratory of Animal Ecological Genomics, Xining, Qinghai, China.
⁷ University of the Chinese Academy of Sciences, Beijing, China.
⁸ Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. zhanxj@ioz.ac.cn.
⁹ Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, Yunnan, China. zhanxj@ioz.ac.cn.
¹⁰ Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China. ybchen@mail.kiz.ac.cn.
¹¹ Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, Yunnan, China. ybchen@mail.kiz.ac.cn.
¹² State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China. ship@mail.kiz.ac.cn.
¹³ Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, Yunnan, China. ship@mail.kiz.ac.cn.
¹⁴ School of Future Technology, University of Chinese Academy of Sciences, Beijing, China. ship@mail.kiz.ac.cn.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Humans
Hypoxia* / genetics
Mutation
Phylogeny
Tibet

Publication types

MeSH terms

Grants and funding