Rice bran, an off-shoot to newer therapeutics in neurological disorders

Biomed Pharmacother. 2021 Aug:140:111796. doi: 10.1016/j.biopha.2021.111796. Epub 2021 Jun 4.

Abstract

Normal brain functioning involves the interaction of interconnected molecular and cellular activities, which appear to alter normal to abnormal brain functioning when worsened, contributing to the emergence of neurological disorders. There are currently millions of people who are living with brain disorders globally and this will rise if suitable prevention strategies are not explored. Nutraceutical intended to treat numerous health goals with little adverse effect possible together can be more beneficial than pharmaceutical monotherapy for fostering balanced brain functioning. Nutraceutical provides a specific composition of effective macronutrients and micronutrients that are difficult to synthesize in the laboratory. Numerous elements of rice fibers in rice bran are characterized as natural anti-oxidant and having potential anti-inflammatory activity. The rice bran captures interest among the researchers as it is widespread, affordable, and rich in nutrients including protein, fat, carbohydrates, bioactive components, and dietary fiber. This review covers the neuroprotective multiplicity of rice bran and its constituents to deter pathological conditions of the brain and to facilitate balanced brain functioning at the same time.

Keywords: Anti-inflammation; Natural anti-oxidant; Neurodegeneration; Nutritional intake; Rice bran; γ-oryzanol.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / therapeutic use*
  • Dietary Supplements
  • Humans
  • Nervous System Diseases / diet therapy*
  • Neuroprotective Agents / therapeutic use*
  • Oryza*
  • Phenylpropionates / therapeutic use*
  • Plant Extracts / therapeutic use*
  • Rice Bran Oil / therapeutic use*
  • Serotonin / metabolism
  • Tocotrienols / therapeutic use*

Substances

  • Anti-Inflammatory Agents
  • Neuroprotective Agents
  • Phenylpropionates
  • Plant Extracts
  • Tocotrienols
  • Tocovid
  • Serotonin
  • Rice Bran Oil
  • gamma-oryzanol