Distinguishing Concerted versus Stepwise Mechanisms Using Isotope Effects on Isotope Effects

Biochemistry. 2021 Nov 23;60(46):3416-3418. doi: 10.1021/acs.biochem.1c00325. Epub 2021 Jun 7.

Authors

Mark W Ruszczycky¹, Hung-Wen Liu^{1

2}

Affiliations

¹ Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, The University of Texas at Austin, Austin, Texas 78712, United States.
² Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States.

No abstract available

Publication types

Historical Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Carbon Isotopes / chemistry*
Carbon Isotopes / metabolism
Chemical Fractionation / methods*
Deuterium / chemistry*
Deuterium / metabolism
History, 20th Century
Isotope Labeling / history
Isotope Labeling / methods*
Kinetics

Substances

Carbon Isotopes
Deuterium
Carbon-13

Grants and funding