Atypical granular cell tumor of the urinary bladder: A case report and literature review

Antonio Tufano; Vittorio Canale; Giovanni Di Lascio; Giulia Coppola; Rocco Simone Flammia; Cristiano Cristini

doi:10.1016/j.eucr.2021.101669

Atypical granular cell tumor of the urinary bladder: A case report and literature review

Urol Case Rep. 2021 Mar 29:38:101669. doi: 10.1016/j.eucr.2021.101669. eCollection 2021 Sep.

Authors

Antonio Tufano¹, Vittorio Canale¹, Giovanni Di Lascio¹, Giulia Coppola², Rocco Simone Flammia¹, Cristiano Cristini¹

Affiliations

¹ Department of Urology, Sapienza University, Rome, Italy.
² Department of Radiological, Oncological and Pathological Sciences, Sapienza University, Rome, Italy.

Abstract

Granular cell tumors (GCTs) are rare neoplasms of neural origin and usually tend to have a benign behaviour. We report a case of a 54 years old woman with severe gross hematuria caused by an atypical granular cell tumor which was successfully managed with a transurethral resection of the bladder (TURB). No local recurrence was observed after a three-year follow-up. The appropriate histological characterization and subclassification (benign, atypical and malignant neoplasm) is mandatory for an optimal patient management, in order to offer an appropriate treatment and a correct follow-up.

Keywords: Bladder neoplasm; Bladder tumor; Granular cell tumor.

Publication types

Case Reports