Pancreatitis after endoscopic retrograde cholangiopancreatography: A narrative review

World J Gastroenterol. 2021 May 28;27(20):2495-2506. doi: 10.3748/wjg.v27.i20.2495.

Abstract

Acute post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is a feared and potentially fatal complication that can be as high as up to 30% in high-risk patients. Pre-examination measures, during the examination and after the examination are the key to technical and clinical success with a decrease in adverse events. Several studies have debated on the subject, however, numerous topics remain controversial, such as the effectiveness of prophylactic medications and the amylase dosage time. This review was designed to provide an update on the current scientific evidence regarding PEP available in the literature.

Keywords: Adverse events; Endoscopic retrograde cholangiopancreatography; Pancreatitis; Post-endoscopic retrograde cholangiopancreatography pancreatitis; Prevention.

Publication types

  • Review

MeSH terms

  • Amylases
  • Cholangiopancreatography, Endoscopic Retrograde* / adverse effects
  • Humans
  • Pancreatitis* / etiology
  • Risk Factors

Substances

  • Amylases