Classical Hodgkin's lymphoma with cutaneous involvement in an adolescent male: A case study

Cancer Rep (Hoboken). 2022 Feb;5(2):e1473. doi: 10.1002/cnr2.1473. Epub 2021 Jun 5.

Abstract

Background: Hodgkin's lymphoma (HL) with skin involvement is reasonably rare. It typically occurs late in the course and is associated with a poor prognosis; however, it may also be indolent in some cases.

Case: We report a case of a 15-year-old previously healthy male with Hodgkin's lymphoma who presented with multiple lymphadenopathies of axilla and serpiginous ulcerative nodular lesions involving pectoral skin. A lymph node biopsy was performed following an initial diagnostic workup for a suspected active infectious disease, which revealed a neoplastic invasion from a mixed cellularity classical HL with skin involvement. A total of six cycles of ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) chemotherapy regimen was administered to the patient.

Conclusion: In comparison to other studies, this case demonstrates that a good response is possible with standard ABVD chemotherapy.

Keywords: ABVD; Hodgkin lymphoma; case report; chemotherapy; cutaneous lesions; lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Biopsy
  • Hodgkin Disease / drug therapy*
  • Hodgkin Disease / pathology*
  • Humans
  • Lymphatic Metastasis
  • Male
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / pathology*
  • Whole Body Imaging