The to and fro of Rho

Kenneth D Westover

doi:10.1016/j.str.2021.05.009

The to and fro of Rho

Structure. 2021 Jun 3;29(6):507-509. doi: 10.1016/j.str.2021.05.009.

Author

Kenneth D Westover¹

Affiliation

¹ Department of Biochemistry, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA; Department of Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA. Electronic address: kenneth.westover@utsouthwestern.edu.

Abstract

The functions of Ras members are largely governed by the structural dynamics of the nucleotide-binding switch regions. In this issue of Structure, Lin et al. (2021) take a close look at the dynamic equilibrium of RhoA, the founding member of the Rho family of Ras GTPases.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

ras Proteins*

Substances

ras Proteins

Grants and funding

R01 CA244341/CA/NCI NIH HHS/United States