A comparison of two pulp revascularization techniques using platelet-rich plasma and whole blood clot

Naren Ramachandran; Shishir Singh; Rajesh Podar; Gaurav Kulkarni; Roshan Shetty; Padmini Chandrasekhar

doi:10.4103/JCD.JCD_221_20

A comparison of two pulp revascularization techniques using platelet-rich plasma and whole blood clot

J Conserv Dent. 2020 Nov-Dec;23(6):637-643. doi: 10.4103/JCD.JCD_221_20. Epub 2021 Feb 11.

Authors

Naren Ramachandran¹, Shishir Singh¹, Rajesh Podar¹, Gaurav Kulkarni¹, Roshan Shetty¹, Padmini Chandrasekhar¹

Affiliation

¹ Department of Conservative Dentistry and Endodontics, Terna Dental College and Hospital, Navi Mumbai, Maharashtra, India.

Abstract

Aim: The aim of this preliminary study was to compare outcomes of two regenerative endodontic protocols in necrotic teeth with open apices.

Methodology: Forty teeth with open apices in patients with an age range of 15-54 were randomly distributed in two groups: group 1, with whole blood clot in the canal (n=20) and group 2, whole blood with Platelet rich plasma (PRP) in the canal (n=20). Clinical and radiological follow up assessments were undertaken over a period ranging from 6 months to one year. Radiographic Root Area (RRA) was measured using the freeware ImageJ. Statistical analysis was performed using the independent samples t test and the Chi-squared test, the significance level was set at p=0.05.

Results: There was no difference in the percentage change in RRA between the PRP group and whole blood-clot + PRP group.

Conclusion: Whole blood clot and PRP are comparable on the grounds of percentage change in RRA and there is no statistically significant difference between the two in a follow-up period of up to one year.

Keywords: Platelet-rich plasma; pulp revascularization; regenerative endodontics.