1 Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, 113‑8510, Japan.
2 Molecular Regulation of Aging, Tokyo Metropolitan Institute of Gerontology, Tokyo, 173‑0015, Japan.
3 Biomedical Gerontology Laboratory, Faculty of Human Sciences, Waseda University, Tokorozawa, 359‑1192, Japan.
4 Department of Molecular and Cellular Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, 113‑8510, Japan.
5 Department of Epigenetics, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo‑ku, Tokyo, 113‑8510, Japan.
6 Laboratory of Embryology and Genomics, Department of Biotechnology, Faculty of Life and Environmental Sciences, University of Yamanashi, Kofu, Yamanashi, 400‑8510, Japan.
7 Department of Molecular and Cellular Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, 113‑8510, Japan. yogawa@med.kyushu-u.ac.jp.
8 Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3‑1‑1 Maidashi, Higashi‑ku, Fukuoka, 812‑8582, Japan. yogawa@med.kyushu-u.ac.jp.
9 Department of Preemptive Medicine and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1‑5‑45 Yushima, Bunkyo‑ku, Tokyo, 113‑8510, Japan. k-hashi@dokkyomed.ac.jp.
10 Department of Diabetes, Endocrinology and Hematology, Dokkyo Medical University Saitama Medical Center, 2‑1‑50 Minami‑Koshigaya, Koshigaya, Saitama, 343‑8555, Japan. k-hashi@dokkyomed.ac.jp.