Precision medicine reaching out to the patients in allergology - a German-Japanese workshop report

Oliver Pfaar; Katharina Blumchen; Eistine Boateng; Eckard Hamelmann; Tomohisa Iinuma; Thilo Jakob; Susanne Krauss-Etschmann; Hiroyuki Nagase; Saeko Nakajima; Taiji Nakano; Harald Renz; Sakura Sato; Christian Taube; Martin Wagenmann; Thomas Werfel; Margitta Worm; Kenji Izuhara

doi:10.5414/ALX02234E

Precision medicine reaching out to the patients in allergology - a German-Japanese workshop report

Allergol Select. 2021 May 27:5:162-179. doi: 10.5414/ALX02234E. eCollection 2021.

Authors

Oliver Pfaar¹, Katharina Blumchen², Eistine Boateng³, Eckard Hamelmann⁴, Tomohisa Iinuma⁵, Thilo Jakob⁶, Susanne Krauss-Etschmann^{3

7}, Hiroyuki Nagase⁸, Saeko Nakajima⁹, Taiji Nakano¹⁰, Harald Renz¹¹, Sakura Sato¹², Christian Taube¹³, Martin Wagenmann¹⁴, Thomas Werfel¹⁵, Margitta Worm¹⁶, Kenji Izuhara¹⁷

Affiliations

¹ Department of Otorhinolaryngology, Head and Neck Surgery, Section of Rhinology and Allergy, University Hospital Marburg, Philipps-Universität Marburg.
² Department of Children and Adolescent Medicine, Division of Pneumology, Allergology and Cystic fibrosis, University Hospital Frankfurt, Goethe University, Frankfurt am Main.
³ Early Life Origins of Chronic Lung Disease, Research Center Borstel, Leibniz Lung Center, Member of the German Center for Lung Research (DZL), Borstel.
⁴ Children's Center Bethel, EvK Bielefeld, University Bielefeld, Bielefeld, Germany.
⁵ Department of Otorhinolaryngology, Head and Neck Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
⁶ Department of Dermatology and Allergology, University Medical Center Giessen (UKGM), Justus Liebig University Giessen.
⁷ Institute for Experimental Medicine, Christian-Albrechts-Universität zu Kiel, Kiel, Germany.
⁸ Division of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School of Medicine, Tokyo.
⁹ Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto.
¹⁰ Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, Japan.
¹¹ Institute of Laboratory Medicine, Philipps University Marburg, Marburg and Universities of Giessen and Marburg Lung Center (UGMLC), Philipps University Marburg, German Center for Lung Research (DZL) Marburg, Marburg, Germany.
¹² Department of Allergy, Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Japan.
¹³ Department of Pulmonary Medicine, University Medicine Essen - Ruhrlandklinik, Essen.
¹⁴ Department of Otorhinolaryngology (HNO-Klinik), Rhinology, Allergy, and endoscopic skull base surgery, Düsseldorf University Hospital (UKD), Düsseldorf.
¹⁵ Department Dermatology and Allergy, Hannover Medical School, Hannover.
¹⁶ Division of Allergology and Immunology, Department Dermatology, Venerology and Allergology, Charité Universitätsmedizin Berlin, Berlin, Germany, and.
¹⁷ Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Japan.

Abstract

An expert workshop in collaboration of the German Society of Allergy and Clinical Immunology (DGAKI) and the Japanese Society of Allergy (JSA) provided a platform for key opinion leaders of both countries aimed to join expertise and to highlight current developments and achievements in allergy research. Key domains of the meeting included the following seven main sections and related subchapters: 1) basic immunology, 2) bronchial asthma, 3) prevention of allergic diseases, 4) food allergy and anaphylaxis, 5) atopic dermatitis, 6) venom allergy, and 7) upper airway diseases. This report provides a summary of panel discussions of all seven domains and highlights unmet needs and project possibilities of enhanced collaborations of scientific projects.

Keywords: allergen immunotherapy; allergic rhinitis; asthma; atopic dermatitis; biologics; insect venom allergy; microbiome.