Environmental Pollution and Peripheral Artery Disease

Risk Manag Healthc Policy. 2021 May 27:14:2181-2190. doi: 10.2147/RMHP.S307150. eCollection 2021.

Abstract

Peripheral artery disease (PAD) of the lower limbs represents one of the most important clinical conditions among vascular disease and can negatively impact quality of life of affected patients, representing also an important socioeconomic burden. Several risk factors predispose to PAD and its complications. Nevertheless, the role of pollution in this context has not been fully evaluated and this article explored the most updated information on epidemiology and environmental pollution in order to hypothesize the possible contribution of air pollution in the onset of PAD. Pollution is an important problem for the global community and has harmful effects on human health and cardiovascular system, and, specifically, particulate matter 10 (PM10) was found significantly associated with PAD.

Keywords: PM10; environment; peripheral artery disease; pollution; risk factors.

Publication types

  • Review

Grants and funding

This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.