Effects of non-invasive respiratory support on gas exchange and outcomes in COVID-19 outside the ICU

Ciara Gough; Michelle Casey; Thomas A McCartan; Alessandro N Franciosi; Derek Nash; Dominic Doyle; Neil Hyland; Grace Kavanagh; Sile Toland; Caleb Powell; Rhea O'Regan; Ruán Ó Conluain; Garrett Greene; Grace Murray; Israa Fathi Hussein; Eoin Hunt; Fatma Gargoum; David Curran; Tidi Hassan; Liam Cormican; Richard W Costello; Tom McEnery

doi:10.1016/j.rmed.2021.106481

Effects of non-invasive respiratory support on gas exchange and outcomes in COVID-19 outside the ICU

Respir Med. 2021 Aug-Sep:185:106481. doi: 10.1016/j.rmed.2021.106481. Epub 2021 May 25.

Authors

Ciara Gough¹, Michelle Casey², Thomas A McCartan³, Alessandro N Franciosi³, Derek Nash⁴, Dominic Doyle⁴, Neil Hyland⁴, Grace Kavanagh⁵, Sile Toland⁶, Caleb Powell⁶, Rhea O'Regan⁷, Ruán Ó Conluain⁸, Garrett Greene⁹, Grace Murray³, Israa Fathi Hussein³, Eoin Hunt¹⁰, Fatma Gargoum⁴, David Curran⁵, Tidi Hassan⁶, Liam Cormican⁷, Richard W Costello², Tom McEnery¹⁰

Affiliations

¹ Royal College of Surgeons in Ireland, Dublin, Ireland; Department of Respiratory Medicine, Beaumont Hospital, Dublin, Ireland. Electronic address: Ciaragough007@gmail.com.
² Royal College of Surgeons in Ireland, Dublin, Ireland; Department of Respiratory Medicine, Beaumont Hospital, Dublin, Ireland.
³ Royal College of Surgeons in Ireland, Dublin, Ireland.
⁴ Department of Respiratory Medicine, University Hospital Galway, Ireland.
⁵ Department of Respiratory Medicine, Mercy Hospital, Cork, Galway, Ireland.
⁶ Department of Respiratory Medicine, Our Lady of Lourdes Hospital, Drogheda, Ireland.
⁷ Department of Respiratory and Sleep Medicine, James Connolly Memorial Hospital, Dublin, Ireland.
⁸ Trinity College Dublin, Ireland.
⁹ Department of Mathematics and Statistics, Royal College of Surgeons, Ireland.
¹⁰ Department of Respiratory Medicine, Mater Misericordiae University Hospital, Dublin, Ireland.

Abstract

Non-invasive respiratory support (NRS) outside of the ICU has played an important role in the management of COVID-19 pneumonia. There is little data to guide selection of NRS modality. We present outcomes of NRS outside the ICU and discuss the effects of NRS on gas exchange with implications for management.

Publication types

Multicenter Study
Observational Study

MeSH terms

Aged
Aged, 80 and over
COVID-19 / epidemiology
COVID-19 / physiopathology
COVID-19 / therapy*
Female
Humans
Intensive Care Units*
Male
Middle Aged
Noninvasive Ventilation / methods*
Pulmonary Gas Exchange / physiology*
SARS-CoV-2*
Treatment Outcome