Ivacaftor and Airway Inflammation in Preschool Children with Cystic Fibrosis

Paul McNally; Daryl Butler; Yuliya V Karpievitch; Barry Linnane; Sarath Ranganathan; Stephen M Stick; Graham L Hall; André Schultz

doi:10.1164/rccm.202012-4332LE

Ivacaftor and Airway Inflammation in Preschool Children with Cystic Fibrosis

Am J Respir Crit Care Med. 2021 Sep 1;204(5):605-608. doi: 10.1164/rccm.202012-4332LE.

Authors

Paul McNally^{1

2}, Daryl Butler^{1

2}, Yuliya V Karpievitch^{3

4}, Barry Linnane^{1

5}, Sarath Ranganathan^{6

7

8}, Stephen M Stick^{3

4

9}, Graham L Hall^{4

10}, André Schultz^{3

4

9}

Affiliations

¹ Children's Health Ireland Dublin, Ireland.
² Royal College of Surgeons in Ireland University of Medicine and Health Sciences Dublin, Ireland.
³ University of Western Australia Perth, Western Australia, Australia.
⁴ Telethon Kids Institute Perth, Western Australia, Australia.
⁵ University of Limerick Limerick, Ireland.
⁶ University of Melbourne Melbourne, Victoria, Australia.
⁷ Royal Children's Hospital Parkville, Victoria, Australia.
⁸ Murdoch Children's Research Institute Parkville, Victoria, Australia.
⁹ Perth Children's Hospital Nedlands, Western Australia, Australia.
¹⁰ Curtin University Bentley, Western Australia, Australia.

PMID: 34077699
DOI: 10.1164/rccm.202012-4332LE

No abstract available

Publication types

Comparative Study
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Age Factors
Airway Obstruction / drug therapy*
Aminophenols / therapeutic use*
Child, Preschool
Chloride Channel Agonists / therapeutic use*
Cystic Fibrosis / drug therapy*
Cystic Fibrosis / genetics
Cystic Fibrosis / physiopathology*
Cystic Fibrosis Transmembrane Conductance Regulator / drug effects
Cystic Fibrosis Transmembrane Conductance Regulator / genetics
Female
Humans
Infant
Inflammation / drug therapy*
Male
Mutation
Quinolones / therapeutic use*

Substances

Aminophenols
Chloride Channel Agonists
Quinolones
Cystic Fibrosis Transmembrane Conductance Regulator