The ATP/P2X7 axis is a crucial regulator of leukemic initiating cells proliferation and homing and an emerging therapeutic target in acute myeloid leukemia

Purinergic Signal. 2021 Sep;17(3):319-321. doi: 10.1007/s11302-021-09789-4. Epub 2021 Jun 1.
No abstract available

Publication types

  • Review

MeSH terms

  • Adenosine Triphosphate / metabolism*
  • Animals
  • Antineoplastic Agents / administration & dosage
  • Cell Proliferation / drug effects
  • Cell Proliferation / physiology*
  • Drug Delivery Systems / methods*
  • Drug Delivery Systems / trends
  • Humans
  • Leukemia, Myeloid, Acute / drug therapy
  • Leukemia, Myeloid, Acute / metabolism*
  • Receptors, Purinergic P2X7 / metabolism*

Substances

  • Antineoplastic Agents
  • Receptors, Purinergic P2X7
  • Adenosine Triphosphate