The natural analgesic conolidine targets the newly identified opioid scavenger ACKR3/CXCR7

Signal Transduct Target Ther. 2021 Jun 2;6(1):209. doi: 10.1038/s41392-021-00548-w.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analgesics, Opioid / chemistry
  • Analgesics, Opioid / pharmacology*
  • Cell Line, Tumor
  • Humans
  • Indole Alkaloids / chemistry
  • Indole Alkaloids / pharmacology*
  • Receptors, CXCR* / antagonists & inhibitors
  • Receptors, CXCR* / genetics
  • Receptors, CXCR* / metabolism
  • Signal Transduction / drug effects*

Substances

  • ACKR3 protein, human
  • Analgesics, Opioid
  • Indole Alkaloids
  • Receptors, CXCR
  • conolidine