Seeing through the evidence for corneal neurotization

Nate Jowett; Roberto Pineda 2nd

doi:10.1097/MOO.0000000000000731

Seeing through the evidence for corneal neurotization

Curr Opin Otolaryngol Head Neck Surg. 2021 Aug 1;29(4):252-258. doi: 10.1097/MOO.0000000000000731.

Authors

Nate Jowett¹, Roberto Pineda 2nd²

Affiliations

¹ Department of Otolaryngology - Head & Neck Surgery.
² Department of Ophthalmology, Massachusetts Eye and Ear and Harvard Medical School, Boston, Massachusetts, USA.

PMID: 34074877
DOI: 10.1097/MOO.0000000000000731

Abstract

Purpose of review: Trigeminal anesthesia causes neurotrophic keratopathy, which may yield facial disfigurement and corneal blindness.

Recent findings: We summarize approaches and evidence for corneal neurotization.

Summary: Regional sensory nerve transfer appears safe and effective for therapeutic management of neurotrophic keratopathy. Prospective randomized clinical trials are necessary to confirm the utility of corneal neurotization.

Publication types

Review

MeSH terms

Cornea / surgery
Corneal Diseases* / surgery
Humans
Nerve Transfer*
Prospective Studies
Trigeminal Nerve Diseases* / surgery