Metabolomics in the Identification of Biomarkers of Asthma

Metabolites. 2021 May 29;11(6):346. doi: 10.3390/metabo11060346.

Alma Villaseñor^{1

2}, Ibon Eguiluz-Gracia^{3

4}, André Moreira^{5

6

7}, Craig E Wheelock^{8

9

10}, María M Escribese¹

¹ Department of Basic Medical Sciences, Facultad de Medicina, Institute of Applied Molecular Medicine (IMMA), Universidad San Pablo CEU, CEU Universities, 28660 Madrid, Spain.
² Centre for Metabolomics and Bioanalysis (CEMBIO), Department of Chemistry and Biochemistry, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte, 28660 Madrid, Spain.
³ Allergy Group, Instituto de Investigacion Biomedica de Malaga (IBIMA) and ARADyAL, 29009 Malaga, Spain.
⁴ Allergy Unit, Hospital Regional Universitario de Malaga, 29009 Malaga, Spain.
⁵ EPI Unit, Instituto de Saúde Pública, Universidade do Porto, 4050-600 Porto, Portugal.
⁶ Serviço de Imunologia Básica e Clínica, Departamento de Patologia, Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal.
⁷ Serviço de Imunoalergologia, Centro Hospitalar São João EPE, 4200-319 Porto, Portugal.
⁸ Division of Physiological Chemistry 2, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Biomedicum Quartier 9A, SE-171-77 Stockholm, Sweden.
⁹ Department of Respiratory Medicine and Allergy, Karolinska University Hospital, SE-171-77 Stockholm, Sweden.
¹⁰ Gunma University Initiative for Advanced Research (GIAR), Gunma University, 3-39-22 Showa-machi, Maebashi 371-8511, Gunma, Japan.

Abstract

Asthma is a major non-communicable disease characterized by recurrent attacks of breathlessness and wheezing [...].