Automated Detection of Hypertension Using Physiological Signals: A Review

Int J Environ Res Public Health. 2021 May 29;18(11):5838. doi: 10.3390/ijerph18115838.

Abstract

Arterial hypertension (HT) is a chronic condition of elevated blood pressure (BP), which may cause increased incidence of cardiovascular disease, stroke, kidney failure and mortality. If the HT is diagnosed early, effective treatment can control the BP and avert adverse outcomes. Physiological signals like electrocardiography (ECG), photoplethysmography (PPG), heart rate variability (HRV), and ballistocardiography (BCG) can be used to monitor health status but are not directly correlated with BP measurements. The manual detection of HT using these physiological signals is time consuming and prone to human errors. Hence, many computer-aided diagnosis systems have been developed. This paper is a systematic review of studies conducted on the automated detection of HT using ECG, HRV, PPG and BCG signals. In this review, we have identified 23 studies out of 250 screened papers, which fulfilled our eligibility criteria. Details of the study methods, physiological signal studied, database used, various nonlinear techniques employed, feature extraction, and diagnostic performance parameters are discussed. The machine learning and deep learning based methods based on ECG and HRV signals have yielded the best performance and can be used for the development of computer-aided diagnosis of HT. This work provides insights that may be useful for the development of wearable for continuous cuffless remote monitoring of BP based on ECG and HRV signals.

Keywords: ANN; BCG signal; CNN; ECG signal; HRV signal; HT ECG signal classification; PPG signal; RNN; deep learning; hypertension; supervised machine learning.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Electrocardiography
  • Heart Rate
  • Humans
  • Hypertension* / diagnosis
  • Monitoring, Physiologic
  • Photoplethysmography*