Alcohol in Psoriasis-From Bench to Bedside

Int J Mol Sci. 2021 May 7;22(9):4987. doi: 10.3390/ijms22094987.

Abstract

Alcohol affects the symptoms, compliance and comorbidities as well as the safety and efficacy of treatments in psoriatic patients. In this review, we aim to summarize and link clinical observations with a molecular background, such as signaling pathways at the cellular level and genetic variations, and to provide an overview of how this knowledge could influence our treatment selection and patient management.

Keywords: addiction; alcohol; compliance; genetic factors; immune cells; keratinocytes; psoriasis.

Publication types

  • Review

MeSH terms

  • Animals
  • Ethanol / adverse effects*
  • Genetic Predisposition to Disease
  • Humans
  • Models, Biological
  • Patient Compliance
  • Psoriasis / genetics
  • Psoriasis / pathology*
  • Psoriasis / therapy
  • Translational Research, Biomedical*

Substances

  • Ethanol