The Role of Monocytes and Macrophages in Homeostasis and Disease and Novel Avenues for Putative Treatments

Int J Mol Sci. 2021 May 6;22(9):4927. doi: 10.3390/ijms22094927.

Malgorzata Kloc^{1

2

3}, Jacek Z Kubiak^{4

5}

¹ Houston Methodist Research Institute, Houston, TX 77030, USA.
² Department of Surgery, Houston Methodist Hospital, Houston, TX 77030, USA.
³ M.D. Anderson Cancer Center, Department of Genetics, University of Texas, Houston, TX 77030, USA.
⁴ Department of Regenerative Medicine and Cell Biology, Military Institute of Hygiene and Epidemiology (WIHE), 01-163 Warsaw, Poland.
⁵ Dynamics and Mechanics of Epithelia Group, Faculty of Medicine, Institute of Genetics and Development of Rennes (IGDR), University of Rennes, CNRS, UMR 6290, 35000 Rennes, France.

Abstract

Macrophages were discovered in the 19th century by Ukrainian biologist Élie Metchnikoff who worked in Ukraine, Russia, and France [...].