A 1-Hydroxy-2,4-Diformylnaphthalene-Based Fluorescent Probe and Its Detection of Sulfites/Bisulfite

Qing Shi; Ling-Yi Shen; Hong Xu; Zhi-Yong Wang; Xian-Jiong Yang; Ya-Li Huang; Carl Redshaw; Qi-Long Zhang

doi:10.3390/molecules26113064

A 1-Hydroxy-2,4-Diformylnaphthalene-Based Fluorescent Probe and Its Detection of Sulfites/Bisulfite

Molecules. 2021 May 21;26(11):3064. doi: 10.3390/molecules26113064.

Authors

Qing Shi¹, Ling-Yi Shen², Hong Xu^{1

2}, Zhi-Yong Wang², Xian-Jiong Yang², Ya-Li Huang², Carl Redshaw³, Qi-Long Zhang^{1

2}

Affiliations

¹ The Key Laboratory of Environmental Pollution Monitoring and Disease Control, School of Public Health, Ministry of Education, Guizhou Medical University, Guiyang 550004, China.
² School of Basic Medical Science, Guizhou Medical University, Guiyang 550004, China.
³ Department of Chemistry, University of Hull, Cottingham Road, Hull HU6 7RX, UK.

Abstract

A novel 1-hydroxy-2,4-diformylnaphthalene-based fluorescent probe L was synthesized by a Knoevenagel reaction and exhibited excellent sensitivity and selectivity towards sulfite ions (SO₃^2-) and bisulfite ions (HSO₃^-). The detection limits of the probe L were 0.24 μM using UV-Vis spectroscopy and 9.93 nM using fluorescence spectroscopy, respectively. Furthermore, the fluorescent probe L could be utilized for detection in real water samples with satisfactory recoveries in the range 99.20%~104.30% in lake water and 100.00%~104.80% in tap water by UV-Vis absorption spectrometry, and in the range 100.50%~108.60% in lake water and 102.70%~103.80% in tap water by fluorescence spectrophotometry.

Keywords: crystal structure; fluorescent probe; real sample detection; sulfite/bisulfite.