Taxonomy of Phleboviruses, Emphasizing Those That Are Sandfly-Borne

Viruses. 2021 May 15;13(5):918. doi: 10.3390/v13050918.

Abstract

Sandfly-borne phleboviruses (phylum Negarnavaricota, realm Riboviria, kingdom Orthornavirae, genus Phlebovirus) comprise three genome segments of ribonucleic acid (RNA) and which encode an RNA-dependent RNA polymerase, which they use to transcribe the viral RNA genome into messenger RNA and to replicate the genome. At least some of these viruses cause mild 3-day fevers in humans but some also have been associated with more severe illnesses in humans. The 67 recognized phleboviruses are listed here in a table composed by the authors from International Committee on Taxonomy of Viruses reports as well as the scientific literature.

Keywords: Phlebovirus; reassortant virus; sand fly; virus species.

MeSH terms

  • Animals
  • Genome, Viral
  • Phlebovirus / classification*
  • Phlebovirus / genetics*
  • Phylogeny*
  • Psychodidae / virology*
  • Reassortant Viruses / classification
  • Reassortant Viruses / genetics