Immunology of Cell Death in Cancer Immunotherapy

Lorenzo Galluzzi; Abhishek D Garg

doi:10.3390/cells10051208

Immunology of Cell Death in Cancer Immunotherapy

Cells. 2021 May 15;10(5):1208. doi: 10.3390/cells10051208.

Authors

Lorenzo Galluzzi^{1

2

3

4

5}, Abhishek D Garg⁶

Affiliations

¹ Department of Radiation Oncology, Weill Cornell Medical College, New York, NY 10065, USA.
² Sandra and Edward Meyer Cancer Center, New York, NY 10065, USA.
³ Caryl and Israel Englander Institute for Precision Medicine, New York, NY 10065, USA.
⁴ Department of Dermatology, Yale School of Medicine, New Haven, CT 06520, USA.
⁵ Université de Paris, 75006 Paris, France.
⁶ Cell Stress & Immunity (CSI) Lab, Department for Cellular & Molecular Medicine (CMM), KU Leuven, 3000 Leuven, Belgium.

Abstract

Over the last two decades, a large volume of studies has established that dying and dead cancer cells exert a potent immunomodulatory effect on their immediate microenvironment, which has a major influence on the anticancer immunity [...].

Keywords: apoptosis; biomarkers; immune-checkpoint blockers; immuno-oncology; inflammation; necroptosis.

Publication types

Editorial
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Cell Death
Disease Models, Animal
Humans
Immunotherapy*
Neoplasms / therapy*
Tumor Microenvironment