Synthesis of partial stabilized cement-gypsum as new dental retrograde filling material

S Sadhasivam; Jung-Chih Chen; S Savitha; Ming-Xiang Hsu; Chung-King Hsu; Chun-Pin Lin; Feng-Huei Lin

doi:10.1016/j.msec.2012.05.004

Synthesis of partial stabilized cement-gypsum as new dental retrograde filling material

Mater Sci Eng C Mater Biol Appl. 2012 Oct 1;32(7):1859-1867. doi: 10.1016/j.msec.2012.05.004. Epub 2012 May 12.

Authors

S Sadhasivam¹, Jung-Chih Chen², S Savitha³, Ming-Xiang Hsu⁴, Chung-King Hsu⁴, Chun-Pin Lin⁵, Feng-Huei Lin⁶

Affiliations

¹ Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan; Division of Medical Engineering Research, National Health Research Institute, Zhunan, Miaoli County, Taiwan.
² Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan; Medical Device Innovation Center, National Cheng Kung University, Tainan,Taiwan.
³ Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan.
⁴ Institute of Materials Science and Engineering, National Taipei University of Technology, Taipei, Taiwan.
⁵ School of Dentistry and Graduate Institute of Clinical Dentistry, College of Medicine, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
⁶ Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan; Division of Medical Engineering Research, National Health Research Institute, Zhunan, Miaoli County, Taiwan. Electronic address: double@ntu.edu.tw.

PMID: 34062667
DOI: 10.1016/j.msec.2012.05.004

Abstract

The study describes the sol-gel synthesis of a new dental retrograde filling material partial stabilized cement (PSC)-gypsum by adding different weight percentage of gypsum (25% PSC+75% gypsum, 50% PSC+50% gypsum and 75% PSC+25% gypsum) to the PSC. The crystalline phase and hydration products of PSC-gypsum were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM) analysis. The handling properties such as setting time, viscosity, tensile strength, porosity and pH, were also studied. The XRD and microstructure analysis demonstrated the formation of hydroxyapatite and removal of calcium dihydrate during its immersion in simulated body fluid (SBF) on day 10 for 75% PSC+25% gypsum. The developed PSC-gypsum not only improved the setting time but also greatly reduced the viscosity, which is very essential for endodontic surgery. The cytotoxic and cell proliferation studies indicated that the synthesized material is highly biocompatible. The increased alkaline pH of the PSC-gypsum also had a remarkable antibacterial activity.

Keywords: Dental materials; Endodontics; Gypsum; Hydroxyapatite; Partial stabilized cement; Setting time.