Treatment of pruritus with botulinum toxin in a pediatric patient with Fox-Fordyce disease

Pediatr Dermatol. 2021 Jul;38(4):950-951. doi: 10.1111/pde.14552. Epub 2021 Jun 1.

Abstract

Fox-Fordyce disease is a chronic pruritic disorder of apocrine sweat glands that is often associated with significantly decreased quality of life. With no definitive cure, affected patients are often treated with topical corticosteroids as first-line therapy, but evidence for treatment of refractory cases is limited. We present an adolescent with Fox-Fordyce disease successfully treated for symptomatic relief with botulinum toxin type A injections. While previously reported in an adult patient, we detail the efficacy of this therapy in a pediatric patient.

Keywords: Fox-Fordyce; botulinum toxin type A.

MeSH terms

  • Adolescent
  • Adult
  • Botulinum Toxins, Type A*
  • Child
  • Fox-Fordyce Disease*
  • Humans
  • Pruritus / drug therapy
  • Quality of Life

Substances

  • Botulinum Toxins, Type A