Cutaneous Manifestations of Diabetes

Med Clin North Am. 2021 Jul;105(4):681-697. doi: 10.1016/j.mcna.2021.04.008.

Abstract

Diabetes mellitus is a significant worldwide health concern and cutaneous manifestations are common. This review describes characteristic skin findings of diabetes, general skin findings related to diabetes, and findings related to diabetes treatment with a focus on clinical presentation, diagnosis, pathophysiology, epidemiology, and treatment. As the prevalence of diabetes continues to rise, cutaneous manifestations of diabetes mellitus likely will be encountered more frequently by physicians in all disciplines including dermatologists and primary care physicians. Accordingly, knowledge regarding the prevention, diagnosis, and management of cutaneous manifestations is an important aspect in the care of patients with diabetes.

Keywords: Acanthosis nigricans; Bullous diabeticorum; Diabetes mellitus; Diabetic dermopathy; Diabetic foot ulcer; Lipodystrophy; Necrobiosis lipoidica; Scleredema diabeticorum.

Publication types

  • Review

MeSH terms

  • Acanthosis Nigricans / etiology
  • Acanthosis Nigricans / pathology
  • Acanthosis Nigricans / therapy
  • Dermatologists / statistics & numerical data
  • Diabetes Complications / pathology*
  • Diabetes Mellitus / epidemiology*
  • Diabetic Foot / etiology
  • Diabetic Foot / pathology
  • Diabetic Foot / therapy
  • Global Health / statistics & numerical data
  • Humans
  • Knowledge
  • Lipodystrophy / etiology
  • Lipodystrophy / pathology
  • Lipodystrophy / therapy
  • Middle Aged
  • Necrobiosis Lipoidica / etiology
  • Necrobiosis Lipoidica / pathology
  • Necrobiosis Lipoidica / therapy
  • Physicians, Primary Care / statistics & numerical data
  • Prevalence
  • Scleredema Adultorum / etiology
  • Scleredema Adultorum / pathology
  • Scleredema Adultorum / therapy
  • Skin Diseases / diagnosis*
  • Skin Diseases / epidemiology
  • Skin Diseases / physiopathology*
  • Skin Diseases / prevention & control*