Contemporary management and treatment strategies for asthma during pregnancy

Expert Rev Respir Med. 2021 Sep;15(9):1149-1157. doi: 10.1080/17476348.2021.1935243. Epub 2021 Jul 8.

Abstract

Introduction: Asthma is one of the most common conditions that afflict pregnant women. Because uncontrolled asthma in pregnancy affects both maternal and offspring outcomes, careful attention to maintaining control of asthma symptoms throughout pregnancy is of critical importance.Areas Covered: Using a search of PUBMED/MEDLINE for 'asthma and pregnancy,' this article will review the current literature regarding epidemiology and course of asthma in pregnancy, the effects of uncontrolled asthma on both the mother and offspring, and provide an overview of the management, both non-pharmacologic and pharmacologic, of asthma in pregnancy.Expert Opinion: There is a lack of adequate safety information for most medications taken during pregnancy. Future research might allow better methods to predict which women will experience worsening during pregnancy. For now, surveillance systems like pregnancy registries or observational cohort studies can provide safety information for medications used during pregnancy.

Keywords: Pregnancy; asthma; biologics; inhaled corticosteroids; management; treatment.

MeSH terms

  • Anti-Asthmatic Agents* / adverse effects
  • Asthma* / diagnosis
  • Asthma* / drug therapy
  • Asthma* / epidemiology
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications* / drug therapy
  • Pregnancy Complications* / epidemiology

Substances

  • Anti-Asthmatic Agents