Chorioretinal Biopsy-Proven Ocular Sarcoidosis in a Patient with a History of B-Cell Lymphoma

Sean T Berkowitz; Anderson L Brock; David A Reichstein

doi:10.1159/000512694

Chorioretinal Biopsy-Proven Ocular Sarcoidosis in a Patient with a History of B-Cell Lymphoma

Case Rep Ophthalmol. 2021 May 11;12(2):438-445. doi: 10.1159/000512694. eCollection 2021 May-Aug.

Authors

Sean T Berkowitz¹, Anderson L Brock², David A Reichstein²

Affiliations

¹ Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
² Tennessee Retina, Nashville, Tennessee, USA.

Abstract

The purpose of this report is to describe biopsy-proven ocular sarcoidosis (OS) in a 67-year-old patient with a history of sarcoidosis and diffuse large B-cell lymphoma (DLBCL). Nonspecific posterior chorioretinal lesions in a patient with prior malignancy necessitated chorioretinal biopsy to rule out metastatic lymphoma. The association between sarcoidosis and malignancy remains unclear and can complicate management of similar patients with nonspecific posterior segment findings. Chorioretinal biopsy may, therefore, be required to rule out malignancy in patients with a leading history.

Keywords: Chorioretinal biopsy; Noncaseating granuloma; Ocular sarcoidosis; Posterior uveitis.

Publication types

Case Reports