Platelet-rich Plasma and Cell Therapy: The New Horizon in Hair Loss Treatment

Aditya K Gupta; Helen J Renaud; Jeffrey A Rapaport

doi:10.1016/j.det.2021.04.001

Platelet-rich Plasma and Cell Therapy: The New Horizon in Hair Loss Treatment

Dermatol Clin. 2021 Jul;39(3):429-445. doi: 10.1016/j.det.2021.04.001. Epub 2021 May 15.

Authors

Aditya K Gupta¹, Helen J Renaud², Jeffrey A Rapaport³

Affiliations

¹ Division of Dermatology, Department of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada; Mediprobe Research Inc., 645 Windermere Road, London, Ontario N5X 2P1, Canada. Electronic address: agupta@mediproberesearch.com.
² Mediprobe Research Inc., 645 Windermere Road, London, Ontario N5X 2P1, Canada.
³ Cosmetic Skin and Surgery Center, 333 Sylvan Avenue, Suite 207, Englewood Cliffs, NJ 07632, USA.

PMID: 34053596
DOI: 10.1016/j.det.2021.04.001

Abstract

Current medicinal therapies for treating hair loss have shortcomes due to variability and ineffectiveness, noncompliance, and adverse effects. The prevalence of hair loss and its associated negative psychological impact have driven research into regenerative medicine approaches, such as platelet-rich plasma (PRP) and cell-based therapies, in an attempt to find alternative, safe, effective, and reproducible treatments. Current research shows promising results from these therapies; however, more robust trials are needed to confirm the reported efficacies of PRP and cell-based therapies. Moreover, standardization of treatment preparation as well as dose and regimen are needed.

Keywords: Alopecia areata; Androgenetic alopecia; Cell therapy; Exosomes; Platelet-rich plasma.

Publication types

Review

MeSH terms

Alopecia* / therapy
Cell- and Tissue-Based Therapy
Humans
Platelet-Rich Plasma*