Salvage Esophagectomy

Surg Clin North Am. 2021 Jun;101(3):467-482. doi: 10.1016/j.suc.2021.03.008.

Abstract

Salvage esophagectomy is an option for patients with recurrent or persistent esophageal cancer after definitive chemoradiation therapy or those who undergo active surveillance after induction chemoradiation therapy. Salvage resection is associated with higher rates of morbidity compared with planned esophagectomy but offers patients with locally advanced disease a chance at improved long-term survival. Salvage resection should be preferentially performed in a multidisciplinary setting by high-volume and experienced surgeons. Technical considerations, such as prior radiation dosage, radiation field, and choice of conduit, should be taken into account.

Keywords: Chemoradiation; Delayed esophagectomy; Neoadjuvant; Outcomes; Planned resection.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma / surgery*
  • Adenocarcinoma / therapy
  • Carcinoma, Squamous Cell / surgery*
  • Carcinoma, Squamous Cell / therapy
  • Chemoradiotherapy
  • Esophageal Neoplasms / surgery*
  • Esophageal Neoplasms / therapy
  • Esophagectomy / methods*
  • Humans
  • Neoadjuvant Therapy
  • Patient Selection
  • Salvage Therapy / methods*
  • Time Factors
  • Treatment Outcome