Diagnosing Secondary and Primary Headache Disorders

Continuum (Minneap Minn). 2021 Jun 1;27(3):572-585. doi: 10.1212/CON.0000000000000980.

Abstract

Purpose of review: This article provides a systematic diagnostic approach to the patient with headache.

Recent findings: The vast majority of patients presenting with headache in clinical practice have a primary headache disorder. The most common primary headache disorder in clinical practice is overwhelmingly migraine. Unfortunately, a substantial proportion of patients with migraine do not receive an accurate diagnosis. In addition, the clinical features of migraine overlap with secondary causes of headache, making a careful history and deliberative evaluation for warning symptoms or signs of a secondary headache disorder of paramount importance.

Summary: The approach to the patient with headache requires knowledge of the diagnostic criteria for primary headache disorders, recognition of the importance of a systematic evaluation for red flags associated with secondary headache disorders, and awareness of the pearls and pitfalls encountered in the diagnostic evaluation of a patient with headache.

Publication types

  • Review

MeSH terms

  • Headache
  • Headache Disorders* / diagnosis
  • Headache Disorders, Primary* / diagnosis
  • Headache Disorders, Secondary* / diagnosis
  • Humans
  • Migraine Disorders* / diagnosis