Factor VIII-antibody structure and membrane binding

Blood. 2021 May 27;137(21):2866-2868. doi: 10.1182/blood.2021010947.

Abstract

The cocrystal structure of antibody 2A9 and factor VIII (fVIII), reported by Gish et al in this issue of Blood, delineates an epitope on the C1 domain and novel mobility of the C2 domain, both relevant to membrane binding.

Publication types

  • Editorial
  • Comment

MeSH terms

  • Antibodies, Monoclonal*
  • Factor VIII*

Substances

  • Antibodies, Monoclonal
  • Factor VIII